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My Ozempic experience since August 2022

J

Jaxxson

New member
Nov 9, 2023
1
0
1
Hello..

I've been on Ozempic since August 2022. Months earlier I had been diagnosed with pre-diabeties. I started going to a local doctor to start trying to manage pre-diabetes..I was put on a few meds (metphormin, jardiance) but my A1C level and sugars were still to high and i was then diagnosed with diabeties..so they started me on .25mg Once week. Once a week. before i was prescribed ozempic i had never even heard of it before and had no idea i would lose weight on it.

1 was a 47yr old male (on disability) at the time I started ozempic. I weighed 285 pounds and my A1C was 13%..after a few months I was bumped up to .5mg once a week. I started to realize I was losing weight, I was grazing allday long and my craving for sweets or food in general disappeared..I was then bumped (bout 6 months from start) up to 1mg ozempic weekly..everything seemed fine..my A1C came way down (under 7%) I lost over 40 pounds. I was feeling alot better not as tired or had more energy and my mood seemed brighter. I never felt hungry anymore or had any kind of cravings. Around March of 2023 I was bumped up to 2mg ozempic once a week. I had some of the common side effects of ozempic, constipation, upset stomach, nausea, but they weren't very bad and seemed to disappear over time until I went up to 2mg. (Mentioned later down the page)

I also need to tell you I see a therapist and a physiologist for depression for about 11 years. I'm on a few different medications and the meds they started me on seemed to work wonders and helped me alot for many years up till end of 2022.

Everything seemed to start unraveling around January 2023.. my depression seemed to get worse by the month, I stopped going out, I started having trouble sleeping, I was distancing myself from everyone including my family. My physiologist and I have a wonderful relationship, I would consider her a friend. I started telling her what was Goin on around March of 2023. So together we started to try and switch up my depression and anxiety meds to try and get some help and relief..nothing seemed to help..Also being on the 2mg ozempic seemed to much for me to handle. I wasn't eating at all, I felt sick all the time, I was getting horrible headaches extremely nauseated. So I got in touch with my diabetes doc and she lowered me back to 1mg. It seems to be helping my nausea a bit and I am eating some again going back down to 1 mg..As far as losing weight I seem to have leveled out at about 245 pounds. (Give or take 3 pounds).

I have been in contact with my physcologist literally 3 days a week or more since August because my depression, anxiety, hopelessness, low energy, basically never leaving home, not talking to anyone except my doctor, it has gotten very very bad. I'm still getting bad headaches and my anxiety is almost intolerable. It's now I should add that since around mid September I have started having suicidal thoughts and ideas. Not so much a full on plan or carrying out anything but the thoughts are there and I can't block them out. I have never ever had these kind of thoughts before. I spoke again to my physcologist Nov 8th and we are both in agreement my latest experiment with new doses and depression meds aren't working. She has suggested that I stop taking Ozempic (Fridays my usual 1mg dose) to see if that helps at all. So starting now I am going to skip taking my ozempic the next 3 weeks. Ozempic has a 7 day half life which means it will take atleast 3 weeks to be out of my system I was told. I don't talk to anyone else how i'm feeling cause i really don't have any close friends, my family wouldn't understand, and sometimes i feel like i'm just being a pain and nobody wants to hear about my dumb depression. (Everyone has depression & anxiety I will be told)

I can't tell you for sure it's the Ozempic that is causing me problems with my mood and depression and suicidal thoughts. I do know I have never ever felt as bad as I do right now and nothing seems to be helping me improve. My doctor is extremely concerned and I'm at the point that I don't really care anymore and feel like giving up trying to feel better, but I'm trying whatever my physcologist suggests.

So in the beginning with ozempic..like I said I had no idea about ozempic before I started taking it so i had zero expectations of what it would do for me. It worked great my sugar numbers got within acceptable range I lost around 40 pounds, my energy level and overall mood seemed alot better. But slowly over time things seemed to start changing not overnight but slowly. I've been on ozempic for about 16 months now. Started on .25mg got all the way up to 2mg now back to 1mg since August of 2023. I am hoping by stopping ozempic completely I start feeling better. I don't know what else to possibly do, I've tried everything. Could it be the Ozempic? I don't know..I've read alot of articles about ozempic over the past year but don't really know what to believe. I guess I will see if anything changes by stopping ozempic completely.

Thanks

JJ
 
A

Amelia

Administrator
Staff member
Jun 21, 2022
52
5
8
Hello dear Jaxxson, I'm glad to see you here, welcome to the forum!

It must have been hard for you to tell your story here. Thank you for that. Wow, while reading it, I was thinking that you must be a very strong person and did everything right. I am familiar with depression...and sometimes we need help of a specialist to cope with it, no matter how strong we think we are. And I'm glad you took that step. I am sorry that you had to go through that many difficulties all at the same time, but you are here meaning you feel better and things will go up from now on. I believe in that!

Although I am not a doctor and can't really tell whether it was Ozempic or not that caused you sickness and headaches and other effects, but I think if one feels better after the termination of the drug use, then this was the drug's effect after all. It would be great if you tell us more about the changes after you finish Ozempic completely.

I have a question though: have you done some tests for vitamins and hormones? Because lately I've come across a podcast with an endocrinologist, who was explaining the importance of sufficient protein and microelements consumption. Shortly, he said that one can fix a lot of mental and physical problems by consuming enough protein and iron, fibre, etc., before jumping right into hormones (well at least in his field, but I am sure it relates to any health condition). Proper diet is very important, I can't deny it. Personally, I was surprised to realize how little protein I was consuming and how much sugar was contained in almost everything I bought from the store!

May I ask about your diet/eating routine? Have you or your physician made any changes in that field? Please share if you are comfortable.
I am glad that you feel better now, JJ and I wish you a better day every day! Feel free to contact me, or post your updates here whenever you feel you need to.

Hugs!
Amelia
 
T

Tori

New member
Apr 11, 2024
1
0
1
Hello..

I've been on Ozempic since August 2022. Months earlier I had been diagnosed with pre-diabeties. I started going to a local doctor to start trying to manage pre-diabetes..I was put on a few meds (metphormin, jardiance) but my A1C level and sugars were still to high and i was then diagnosed with diabeties..so they started me on .25mg Once week. Once a week. before i was prescribed ozempic i had never even heard of it before and had no idea i would lose weight on it.

1 was a 47yr old male (on disability) at the time I started ozempic. I weighed 285 pounds and my A1C was 13%..after a few months I was bumped up to .5mg once a week. I started to realize I was losing weight, I was grazing allday long and my craving for sweets or food in general disappeared..I was then bumped (bout 6 months from start) up to 1mg ozempic weekly..everything seemed fine..my A1C came way down (under 7%) I lost over 40 pounds. I was feeling alot better not as tired or had more energy and my mood seemed brighter. I never felt hungry anymore or had any kind of cravings. Around March of 2023 I was bumped up to 2mg ozempic once a week. I had some of the common side effects of ozempic, constipation, upset stomach, nausea, but they weren't very bad and seemed to disappear over time until I went up to 2mg. (Mentioned later down the page)

I also need to tell you I see a therapist and a physiologist for depression for about 11 years. I'm on a few different medications and the meds they started me on seemed to work wonders and helped me alot for many years up till end of 2022.

Everything seemed to start unraveling around January 2023.. my depression seemed to get worse by the month, I stopped going out, I started having trouble sleeping, I was distancing myself from everyone including my family. My physiologist and I have a wonderful relationship, I would consider her a friend. I started telling her what was Goin on around March of 2023. So together we started to try and switch up my depression and anxiety meds to try and get some help and relief..nothing seemed to help..Also being on the 2mg ozempic seemed to much for me to handle. I wasn't eating at all, I felt sick all the time, I was getting horrible headaches extremely nauseated. So I got in touch with my diabetes doc and she lowered me back to 1mg. It seems to be helping my nausea a bit and I am eating some again going back down to 1 mg..As far as losing weight I seem to have leveled out at about 245 pounds. (Give or take 3 pounds).

I have been in contact with my physcologist literally 3 days a week or more since August because my depression, anxiety, hopelessness, low energy, basically never leaving home, not talking to anyone except my doctor, it has gotten very very bad. I'm still getting bad headaches and my anxiety is almost intolerable. It's now I should add that since around mid September I have started having suicidal thoughts and ideas. Not so much a full on plan or carrying out anything but the thoughts are there and I can't block them out. I have never ever had these kind of thoughts before. I spoke again to my physcologist Nov 8th and we are both in agreement my latest experiment with new doses and depression meds aren't working. She has suggested that I stop taking Ozempic (Fridays my usual 1mg dose) to see if that helps at all. So starting now I am going to skip taking my ozempic the next 3 weeks. Ozempic has a 7 day half life which means it will take atleast 3 weeks to be out of my system I was told. I don't talk to anyone else how i'm feeling cause i really don't have any close friends, my family wouldn't understand, and sometimes i feel like i'm just being a pain and nobody wants to hear about my dumb depression. (Everyone has depression & anxiety I will be told)

I can't tell you for sure it's the Ozempic that is causing me problems with my mood and depression and suicidal thoughts. I do know I have never ever felt as bad as I do right now and nothing seems to be helping me improve. My doctor is extremely concerned and I'm at the point that I don't really care anymore and feel like giving up trying to feel better, but I'm trying whatever my physcologist suggests.

So in the beginning with ozempic..like I said I had no idea about ozempic before I started taking it so i had zero expectations of what it would do for me. It worked great my sugar numbers got within acceptable range I lost around 40 pounds, my energy level and overall mood seemed alot better. But slowly over time things seemed to start changing not overnight but slowly. I've been on ozempic for about 16 months now. Started on .25mg got all the way up to 2mg now back to 1mg since August of 2023. I am hoping by stopping ozempic completely I start feeling better. I don't know what else to possibly do, I've tried everything. Could it be the Ozempic? I don't know..I've read alot of articles about ozempic over the past year but don't really know what to believe. I guess I will see if anything changes by stopping ozempic completely.

Thanks

JJ
Hi JJ,

I have never experienced depression from Ozempic, and I have been on it for a year. If anything, it has given me a little boost. I feel a bit more interested in work and a bit more focused on the day that I take it. You might ask your doctor to test your blood folate (Vitamin B9) level.

My internal medicine doctor tested my blood B9 a couple years ago, because I was fatigued. The test came back low. I was already taking extra vitamin B9 because a gene test about 10 years ago revealed one bad copy of my MTHRF gene, which functions to break down vitamin B9 to a usable form. Everyone has two copies of this gene, one from each parent, so I had one good copy and one bad one. As a result, the internist told me to almost triple the amount of my B9 supplement.

I noticed immediate changes, including better mood and better sleep. Also, the tingling and itching of my fingers stopped right away and I stopped having cramps in my legs and feet at night. B9 does not stay in the body very long, the kidneys excrete it, so I now divide my dose to half in the evening and half in the morning. This ensures better focus in the daytime and no cramps at night.

I just wanted to mention this because I have had depression in the past, and my heart goes out to you for this reason. This MTHFR mutation is very common, and may be present in 30% - 40% of Americans. So there is a chance that you could find some help for your depression with a simple blood test for vitamin B9 (folate).

Another good practice I have learned for depression is to tell yourself every morning, "It's going to be a great day!" Then every evening stop and think of one thing that was good during the day. It trains your mind to expect good things.